PSI implements solutions at the local level that have a global impact.

More than 40 percent of the world's population is at risk of malaria. PSI is at the forefront of the global malaria control effort, collaborating with local partners and national ministries of health to implement malaria control programs in more than 30 countries around the world. This support allows ministries of health to scale up effective, evidence-based interventions and sustain coverage over time.

On April 1, 2009, PSI/Uganda officially transitioned into a locally registered organization called the Programme for Accelerated Health, Communication and Education (PACE).